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GLP1 Induced Constipation and Nutraceuticals to Help!

GLP-1 RA medications such as Semaglutide (Ozempic/Wegovy), Tirzepatide (Mounjaro), etc.  have some common side effects (>10%) including but not limited to;Nausea, constipation, or diarrhea, loss of appetite/feeling of fullness and acid reflux.Over time this, like other side effects associated with GLP-1 RA medications will improve in time (usually 2-4 weeks after a dose increase). If some of these side effects are left untreated and become severe, serious health consequences can occur, including renal failure and even death. We have compiled some specific recommendations that we hope you find helpful in managing some of these side effects should you suffer from any of them. 

What should you eat and drink if you are constipated?

Fiber: depending on your age and gender, adults should get between 22-34gm of fiber per day.

Drink plenty of water and other liquids, avoid letting yourself get dehydrated and avoid processed foods.

Good sources of fiber

Whole grains like oatmeal, whole wheat bread or bran flakes.

Legumes: black beans, lentils and soybeans are a few examples

Fruits: berries, apples with the skin on, oranges and pears

Nuts: almonds, peanuts and pecans.

Constipation Support Protocol

Reacted Magnesium “The Mush”Provides Three Forms of Highly Absorbed Magnesium for a Variety of ProtocolsHigh-Concentration Magnesium for Cardiovascular SupportHelps Maintain Healthy Blood Pressure and Glucose LevelsPromotes Energy Production and Muscle Relaxation

Fiber PlusSupports Bowel RegularityHelps With Occasional ConstipationSupports Blood Sugar BalanceMaintains Healthy Cholesterol Levels Already Within the Normal Range

Motility Pro “The Push”Combination of Ginger and Artichoke Leaf Extract that stimulates gastric motility and emptyingPromotes contractions in the migrating motor complex, helping restore proper motility, which ensures steady flow of food particles and bacteriaImproves digestion and relief from gas, bloating and associated GI discomfort

Types of laxatives/Softeners available over the counter

  • Bulk forming laxatives: Metamucil (Psyllium): is a bulk forming laxative: may take up to 1 tablespoon 3 times a day, this may take 12-72 hours for onset of action to occur.

  • Osmotic agents: Miralax: is an osmotic agent, meaning this medication helps pull water back into your colon, softening your stool. May take 1 capful dissolved in 8 ounces of liquid once to twice daily. This may take 1-2 days to produce a bowel movement.  Magnesium citrate.

  • Stool softener: Docusate sodium: is a stool softener. May take 100mg 1 to 2 times per day. This may take 24-48 hours to produce results.

  • Stimulant laxatives: Senna: is a stimulant laxative; it affects electrolyte transport across the intestinal mucosa and enhances colonic transport and motility. Stimulants have the potential to cause some abdominal discomfort/cramping. 

Amino Acids: L-Glutamine: is an amino acid. Amino acids are molecules that play many roles in the body.Their main purpose is to serve as building blocks for proteins. Proteins are crucial to the organs. They also serve other functions, such as transporting substances in the blood and fighting off harmful viruses and bacteria .Glutamine’s immune system benefits are related to its role in intestinal health.Your intestines are a major part of your immune system. Glutamine is an energy source for intestinal and immune cells. It also helps maintain the barrier between the intestines and the rest of your body and aids with proper growth of intestinal cells. You can take L-Glutamine orally or we also offer it as an intramuscular injection.

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