Orthopedic Joint Injections

At Nervana Medical, we specialize in advanced orthopedic joint injections in Sandy, UT, designed to relieve pain, improve mobility, and support long-term joint health. Our treatments include hyaluronic acid (HA) injections, which help lubricate and cushion joints affected by osteoarthritis, and platelet-rich plasma (PRP) injections, which use your body’s own growth factors to promote natural healing and tissue repair. These non-surgical therapies are commonly used for knee, hip, and shoulder pain and can be an excellent option for patients looking to delay or avoid more invasive procedures. By offering both HA and PRP joint injections, our team tailors treatment plans to your specific needs, helping you return to the activities you love with reduced discomfort and improved function.

Studies show that a dual approach is best-

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Who Can Benefit from Orthopedic Joint Injections?

Many patients turn to joint pain injections in Sandy, UT, when daily movement becomes difficult or painful. Common reasons to consider treatment include:

Osteoarthritis that causes stiffness or swelling
Patients seeking non-surgical options before considering joint replacement

If you’ve tried conservative treatments such as physical therapy or over-the-counter pain relievers without success, orthopedic joint injections may provide the targeted relief you need.

Injection types here:

PRP/PRF Joint Injections

PRP/PRF Joint Injections use your body’s own platelets …

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Supartz FX HA Knee Injection

Hyaluronic Acid (HA) Injections provide cushioning and lubrication …

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Durolane Knee Injections

Durolane HA Knee Injections deliver a single, long-lasting …

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What to Expect from Your Treatment

During your consultation, our providers will review your medical history, evaluate the affected joint, and recommend the injection best suited to your needs. Most joint pain injections are completed at our Sandy, UT, office in less than an hour, with minimal downtime. Many patients are able to resume regular activity the same day, making this a convenient solution for busy lifestyles.

Why Nervana Medical for Orthopedic Joint Injections?

Unlike one-size-fits-all pain treatments, our approach combines advanced biologic therapies with personalized care. By offering PRP and HA injections, we create customized plans aligning with your goals for pain relief, mobility, and long-term joint health.

Patients trust Nervana Medical for:

Board-certified providers with expertise in biologic therapies
A comprehensive range of non-surgical options
Convenient telehealth access for follow-up care
A patient-first approach that prioritizes safety and results

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Why Combine Joint PRP + Hyaluronic Acid (HA)

PRP supplies growth factors from your own blood to support tissue healing and regeneration. HA (hyaluronic acid) improves joint lubrication and shock absorption for smoother movement. Together they target both the biology of joint irritation and the mechanics of motion.

Who Can Benefit

Mild–moderate knee osteoarthritis
Activity-related pain, stiffness, or swelling
Patients wanting a longer-lasting, non-steroid option

What to Expect

Same-day PRP + HA injection
Light activity for 24–48 hours
Gradual improvement over 4–12 weeks

FAQs for Orthopedic Joint Injections

1. What is knee osteoarthritis and why does it cause pain?
Knee osteoarthritis occurs when the cartilage in the joint wears down over time. As the bones begin to rub together, it leads to pain, stiffness, swelling, and reduced mobility. Bone spurs may also form as the condition progresses.
2. When should I consider joint injection therapy for knee OA?
If lifestyle changes, physical therapy, and medication no longer provide enough relief, joint injections may help reduce inflammation, improve mobility, and delay or prevent the need for surgery
3. What are hyaluronic acid (HA) injections and how do they work?
HA injections like Durolane® and Supartz® mimic your natural joint fluid, providing lubrication and cushioning in the knee. They are typically recommended for mild to moderate osteoarthritis and can offer relief for 6–12 months.
4. How does PRP therapy help with knee osteoarthritis?
RP uses a concentrated portion of your own blood platelets rich in growth factors. When injected into the knee, it supports tissue healing, reduces inflammation, and may slow the progression of osteoarthritis.
5. Why combine PRP with hyaluronic acid?
Research shows that using PRP and HA together may provide better pain relief and improved joint function compared to either treatment alone. The combination offers lubrication (HA) plus regenerative support (PRP), addressing both symptoms and underlying degeneration.
6. What treatment options does Nervana Medical offer for knee OA?
We create personalized plans that may include Durolane® (single injection), Supartz® (series of injections), PRP alone, or PRP paired with HA. We also provide rehab guidance to support long-term joint health.
7. What is the WOMAC score and why do you use it?
The WOMAC score is a validated questionnaire that measures pain, stiffness, and physical function in people with osteoarthritis. We use it to track your progress and ensure your treatment plan is delivering measurable improvements.
8. How do I know if PRP, HA, or combination therapy is right for me?
During your consultation, we evaluate your symptoms, imaging, and daily activity goals. Based on these findings, we determine whether PRP, HA, or a combination of both will offer the best relief and functional improvement.

Contact Us

At Nervana Medical, we offer a range of advanced biologic treatments for skin rejuvenation, hair restoration in Utah, sexual wellness, and joint pain management. Our team of experts will work with you to develop a customized treatment plan that addresses your specific concerns and helps you achieve your desired results.

Not sure if this treatment is right for you? Contact us today to schedule a consultation and learn more about orthopedic joint injections in Sandy, UT.

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Studies/Current Medical Literature (as of October 2025)

The American Academy of Orthopaedic Surgeons states that both platelet-rich plasma (PRP) and hyaluronic acid (HA) injections may reduce pain and improve function in patients with symptomatic knee osteoarthritis, but the strength of recommendation for PRP is limited due to safety concerns and variability in study results.[1]

The guideline notes that PRP may provide longer-lasting improvement in pain and function compared to HA, with PRP effects persisting beyond 6 months while HA benefits tend to diminish after that period. However, both treatments show similar efficacy at the 6-month mark. The standard practice for HA is injection every six months for painful knee osteoarthritis. The recommendation for PRP is downgraded due to questions about safety (notably, some studies reported grade ≥3 toxicity) and the need for further evaluation.[1]

American Academy of Orthopaedic Surgeons

Management of Osteoarthritis of the Knee (Non-Arthroplasty): Evidence-Based Clinical Practice Guideline

Published August 2021

Building on the guideline recommendations, recent meta-analyses and randomized controlled trials provide further insight into the comparative efficacy and safety of PRP and HA for joint conditions, particularly knee osteoarthritis. Multiple high-quality studies consistently demonstrate that PRP offers superior pain relief and functional improvement compared to HA, with benefits persisting up to 12 months.[2-6] PRP is especially effective in patients with mild-to-moderate disease and younger age groups, and leukocyte-poor PRP formulations may yield better outcomes and fewer adverse events than leukocyte-rich PRP.[2-3]

Combination therapy with PRP and HA has also been investigated. PRP plus HA appears to provide greater pain reduction and functional improvement than HA alone, but does not outperform PRP monotherapy.[7-10] The sequence and protocol of injections may influence outcomes, and combination approaches may be associated with a lower risk of adverse events compared to PRP alone.[7]

For HA, the evidence supports modest improvements in pain and function, with the greatest benefit seen in patients with early-stage osteoarthritis, older women, and those with higher baseline symptom severity.[10-12] The effect of HA typically plateaus at around two months post-injection, and its clinical impact is less pronounced than PRP, though it remains a safe option with a favorable side effect profile.[11-12]

In summary, PRP is generally more effective than HA for pain and function in knee osteoarthritis, and combination therapy may be considered for select patients. Both treatments are safe, but PRP may offer longer-lasting benefits, particularly in early disease and with optimized protocols.[2-6][10]

1. Management of Osteoarthritis of the Knee (Non-Arthroplasty): Evidence-Based Clinical Practice Guideline.

American Academy of Orthopaedic Surgeons (2021)

Practice Guideline

2. Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Belk JW, Kraeutler MJ, Houck DA, et al.

The American Journal of Sports Medicine. 2021;49(1):249-260. doi:10.1177/0363546520909397.

3. Are Leukocyte-Poor or Multiple Injections of Platelet-Rich Plasma More Effective Than Hyaluronic Acid for Knee Osteoarthritis? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Kim JH, Park YB, Ha CW.

Archives of Orthopaedic and Trauma Surgery. 2023;143(7):3879-3897. doi:10.1007/s00402-022-04637-5.

4. Platelet-Rich Plasma Versus Hyaluronic Acid in the Treatment of Knee Osteoarthritis: A Meta-Analysis of 26 Randomized Controlled Trials.

Tan J, Chen H, Zhao L, Huang W.

Arthroscopy : The Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2021;37(1):309-325. doi:10.1016/j.arthro.2020.07.011.

5. Platelet-Rich Plasma Is More Effective Than Hyaluronic Acid Injections for Osteoarthritis of the Knee: A Meta-Analysis Based on Randomized, Double-Blinded, Controlled Clinical Trials.

Li YF, Xing HH, Wei CK, et al.

New Research

6. Recent Advances in Platelet-Rich Plasma Therapy for Osteoarthritis: Mechanisms and Clinical Efficacy.

Cai L, Chen J, Yuan Q, et al.

Journal of Materials Chemistry. B. 2025;. doi:10.1039/d5tb00394f.

Leading Journal New Research

7. The Efficacy and Safety of Intra-Articular Platelet-Rich Plasma Versus Sodium Hyaluronate for the Treatment of Osteoarthritis: Meta-Analysis.

Liu Q, Ye H, Yang Y, Chen H.

PloS One. 2025;20(3):e0314878. doi:10.1371/journal.pone.0314878.

8. Treating Knee Osteoarthritis With Platelet-Rich Plasma and Hyaluronic Acid Combination Therapy: A Systematic Review.

Baria MR, Vasileff WK, Borchers J, et al.