Ketamine Therapy Consultation in Sandy, UT

At Nervana Medical, we require a consultation to assess whether you’re a good candidate for ketamine infusion treatment for depression, anxiety, PTSD, and other mental health conditions. You will meet with a member of our experienced medical team to ensure this treatment is safe for you.

Ketamine Treatment Appointment Instructions

  1. Please have someone available to drive you home after the infusion
  2. Plan to be at the clinic 1.5 hours minimum for a 40 min infusion or 5 hours for a 4-hour infusion
  3. Please do not eat 8 hours before the infusion
  4. You may drink 2 hours before the infusion
  5. Avoid benzodiazepines (for example, Xanax and Ativan) and marijuana on the day of your procedure
  6. Do not take opioid pain medications 6 hours before the procedure

We recommend finding a soothing music playlist to listen to during your infusion, as it can help with its calming effects. We recommend music specific to psychedelic ketamine therapy. You are welcome to bring your own headphones, eye mask, and blanket as well, though we will have these accommodations available should you need them.

Ketamine Patient FAQs

Ketamine is approved by the FDA for use in children and adults for anesthesia and as a pain reliever during medical procedures. Ketamine has an excellent safety record and several applications in medicine: since 1970, it has been a successful anesthetic used in hospitals, dentist offices, and veterinary practices. In the past 10 years, Ketamine has also been identified as having beneficial effects on patients with depression, suicidal ideation, and certain neuropathic pain syndromes.

Ketamine Scheduling/Survey Information

We track your progress by administering three simple surveys before each ketamine treatment in Sandy. The three surveys we utilize are: a self-assessed mood score, a more in-depth PHQ-9 to benchmark and monitor overall depression symptoms, and the GAD generalized anxiety disorder survey. Please answer the questions to the best of your ability, as we actively collect data to continue improving future research/best practice standards, and protocols.

After completing your initial paperwork and first survey, you will need to schedule a medical history and exam clearance appointment prior to your first infusion. The cost of this exam is $50 and does not include lab costs if labs are indicated (primarily for patients with a history of extensive comorbidities or those interested in chronic pain infusion therapy). If you and the provider decide to pursue a series of six infusions, the $50 exam fee is applied to the cost of the infusions. If you have had a recent physical exam, then you are welcome to email it to us for our review, and this fee will be waived.

Scheduling

Our mental health protocol recommends 6 infusions over 2 weeks (please ensure you are able to block off time to ensure you are able to complete the recommended protocol). If you desire your current therapist to be present during the infusion for psychotherapy assistance, you will need to arrange that with them. If they are unable to attend but you would still like psycho assisted therapy during your infusion, then we are happy to provide you with referrals (the price of this would be dependent upon the therapist).

  • Appointment 1 – Medical History and Exam/Clearance
  • Appointment 2 – Infusion #1
  • Appointment 3 – Infusion #2
  • Appointment 4 – Infusion #3
  • Appointment 5 – Infusion #4
  • Appointment 6 – Infusion #5
  • Appointment 7 – Infusion #6

We will provide you with a recommended book list that we find useful to accompany your infusions as you pursue the journey of improving your mental health. Please consider looking into these books in further detail, as they can be beneficial in your overall progress.

Nervana’s Ketamine Mental Health Protocol Rationale

Ketamine side effects include nausea and headaches. We utilize Zofran ODT + IV for a few reasons; Zofran ODT is helpful if the patient is receiving NAD+ IM, as side effects of NAD+ are similar to a niacin rush, including abdominal cramping/bloating.

Toradol is used to mitigate headaches, as with the additional IVF (for when we infuse an entire liter rather than 50 ml on the syringe pump). Most patients who experience headaches from ketamine seem to be more on the dehydrated side, which isn’t uncommon if they’ve been NPO for a while (scheduled towards the end of the day).

Magnesium is an essential cation involved in many functions within the central nervous system, including transmission and intracellular signal transduction. Several studies have shown its usefulness in neurological and psychiatric diseases. Furthermore, it seems that magnesium levels are lowered in the course of several mental disorders, especially depression.

Growing evidence points to the role of vitamin D in the pathobiology and treatment of depression.Many people who have depression may also have low circulating levels of vitamin D in their blood. However, research findings on this potential link are mixed. More research is needed.

How does ketamine help to reduce inflammation? It turns out that ketamine acts on the “kynurenine pathway” in the brain (Kopra et al., 2021), which is responsible for synthesizing the helper molecule (coenzyme) NAD+ from tryptophan found in protein in our diet.

Ketamine and NAD+ are both important for keeping the kynurenine pathway in a healthy “neuroprotective” mode that guards brain cells against damage (Ogyu et al., 2018). When this pathway gets out of balance, brain cells are exposed to harmful “oxidative stress”, which can lead to inflammation and depression.

Some scientists believe that a root cause of a range of mental health disorders, including depression, is depletion of NAD+ stores in cells (Morris et al., 2020). This lack of NAD+ leads to “bioenergetic failure” — causing increased oxidative stress, inflammation, and potentially depression.

Keeping NAD+ stores topped up could therefore be an important defense against depression. Along with natural ways to boost NAD+, both NAD+ supplements and intravenous (IV) NAD+ injections have been shown to be effective for raising NAD+ levels in the body (Grant et al., 2019; Yoshino et al., 2021).

In combination, NAD+ and ketamine treatment in Sandy could help to treat depression by reducing oxidative stress and inflammation. The kynurenine pathway seems to be the critical link between the two, and scientists are continuing to study its role in depression (Ogyu et al., 2018; Kopra et al., 2019)

As this research progresses, traditional antidepressants targeting the serotonin system are being complemented by novel approaches, such as NAD+ and ketamine treatment in Sandy. Building on the hard work of many scientists, these breakthrough treatments are offering new hope to people worldwide who suffer from depression.

Please do not hesitate to contact us if you have any questions at all.

References:

Eby GA, Eby KL. Rapid recovery from major depression using magnesium treatment. Med Hypotheses. 2006;67(2):362-70. doi: 10.1016/j.mehy.2006.01.047. Epub 2006 Mar 20. PMID: 16542786.

Eby GA 3rd, Eby KL. Magnesium for treatment-resistant depression: a review and hypothesis. Med Hypotheses. 2010 Apr;74(4):649-60. doi: 10.1016/j.mehy.2009.10.051. Epub 2009 Nov 27. PMID: 19944540.

Menon V, Kar SK, Suthar N, Nebhinani N. Vitamin D and Depression: A Critical Appraisal of the Evidence and Future Directions. Indian J Psychol Med. 2020 Jan 6;42(1):11-21. doi: 10.4103/IJPSYM.IJPSYM_160_19. PMID: 31997861; PMCID: PMC6970300.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352515

Berman, R. M., Cappiello, A., Anand, A., Oren, D. A., Heninger, G. R., Charney, D. S., & Krystal, J. H. (2000). Antidepressant effects of ketamine in depressed patients. Biological Psychiatry, 47(4), 351-354.https://doi.org/10.1016/S0006-3223(99)00230-9

Beurel, E., Toups, M., & Nemeroff, C. B. (2020). The bidirectional relationship of depression and inflammation: double trouble. Neuron, 107(2), 234-256. https://doi.org/10.1016/j.neuron.2020.06.002

Dell’Osso, L., Carmassi, C., Mucci, F., & Marazziti, D. (2016). Depression, serotonin and tryptophan. Current Pharmaceutical Design, 22(8), 949-954. https://doi.org/10.2174/1381612822666151214104826

Grant, R., Berg, J., Mestayer, R., Braidy, N., Bennett, J., Broom, S., & Watson, J. (2019). A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD. Frontiers in Aging Neuroscience, 11, 257. https://doi.org/10.3389/fnagi.2019.00257

Kopra, E., Mondelli, V., Pariante, C., & Nikkheslat, N. (2021). Ketamine’s effect on inflammation and kynurenine pathway in depression: A systematic review. Journal of Psychopharmacology, 35(8), 934-945.https://doi.org/10.1177/02698811211026426

Krystal, J. H., Abdallah, C. G., Sanacora, G., Charney, D. S., & Duman, R. S. (2019). Ketamine: a paradigm shift for depression research and treatment. Neuron, 101(5), 774-778. https://doi.org/10.1016/j.neuron.2019.02.005

Morris, G., Walder, K. R., Berk, M., Marx, W., Walker, A. J., Maes, M., & Puri, B. K. (2020). The interplay between oxidative stress and bioenergetic failure in neuropsychiatric illnesses: can we explain it and can we treat it?. Molecular Biology Reports, 47(7), 5587-5620. https://doi.org/10.1007/s11033-020-05590-5

National Institute of Mental Health (2022). Major depression. National Institute of Mental Health. Retrieved February 24, 2022, from https://www.nimh.nih.gov/health/statistics/major-depression

Ogyu, K., Kubo, K., Noda, Y., Iwata, Y., Tsugawa, S., Omura, Y., … & Nakajima, S. (2018). Kynurenine pathway in depression: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews, 90, 16-25. https://doi.org/10.1016/j.neubiorev.2018.03.023

Roy, A., & Campbell, M. K. (2013). A unifying framework for depression: bridging the major biological and psychosocial theories through stress. Clinical and Investigative Medicine, E170-E190. https://doi.org/10.25011/cim.v36i4.19951

Wilkinson, S. T., Toprak, M., Turner, M. S., Levine, S. P., Katz, R. B., & Sanacora, G. (2017). A survey of the clinical, off-label use of ketamine as a treatment for psychiatric disorders. American Journal of Psychiatry, 174(7), 695-696. https://doi.org/10.1176/appi.ajp.2017.17020239

Yoshino, M., Yoshino, J., Kayser, B. D., Patti, G. J., Franczyk, M. P., Mills, K. F., … & Klein, S. (2021). Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science, 372(6547), 1224-1229. https://doi.org/10.1126/science.abe9985

Contact Us

Monday: 9:00 AM - 6:00 PM
Tuesday: 9:00 AM - 6:00 PM
Wednesday: 9:00 AM - 7:00 PM
Thursday: 10:00 AM - 6:00 PM
Friday: 10:00 AM - 6:00 PM
Saturday: Closed
Sunday: Closed

Get In Touch

*All indicated fields must be completed.
Please include non-medical questions and correspondence only.

Accessibility Toolbar

Scroll to Top