This is your full O-Shot® (PRP/PRF) Pre + Post Care Guide — read it carefully before and after your appointment. You can also download the printable PDF version to take home.
What Is the O-Shot?
The O-Shot is a regenerative treatment using Platelet-Rich Plasma (PRP) or Platelet-Rich Fibrin (PRF) derived from your own blood. Growth factors are concentrated and injected into specific areas of the vulva and vaginal tissue to support:
- Improved sexual arousal and sensation
- Enhanced lubrication
- Stronger orgasms
- Reduced urinary leakage
- Improved tissue health and blood flow
Because the treatment uses your own platelets, it is natural and biocompatible.
How Does PRP/PRF Work?
Platelets contain growth factors that stimulate:
- Collagen production
- Increased blood supply
- Nerve sensitivity
- Tissue regeneration
PRF differs slightly from PRP in that it releases growth factors more gradually and contains fibrin scaffolding, potentially enhancing longevity.
What Areas Are Treated?
Typically:
- Clitoral complex
- Upper vaginal wall (G-spot region)
Local numbing is applied prior to injections to minimize discomfort.
When Will I Notice Results?
- Some patients notice increased sensitivity within a few weeks.
- Peak results typically occur around 6–12 weeks.
- Results may last 9–18 months depending on individual factors.
How Should I Prepare for My O-Shot?
5–7 Days Before Treatment
Avoid medications and supplements that increase bleeding risk unless medically necessary:
- Aspirin
- Ibuprofen (Motrin®, Advil®)
- Naproxen (Aleve®)
- Fish oil
- Vitamin E
- Garlic supplements
- Gingko biloba
- Flax oil
If you take prescription blood thinners, consult your prescribing provider.
3 Days Before Treatment
- Avoid alcohol.
- Minimize caffeine.
- Avoid smoking (smoking impairs healing and reduces effectiveness).
- Increase hydration (at least 64 oz water daily).
Day of Treatment
- Eat a light meal (do not fast).
- Stay well hydrated.
- Shower beforehand.
- Avoid intercourse the morning of your procedure.
- Wear comfortable clothing.
What Should I Expect After Treatment?
Most patients return to normal activity immediately. Mild temporary effects are common.
Normal Post-Treatment Symptoms
- Mild swelling
- Tenderness
- Bruising
- Sensitivity
- Light spotting
These typically resolve within a few days.
Post-Treatment Instructions
First 6–8 Hours
- Do not touch or manipulate the treated area.
- Avoid applying lotions or creams unless directed.
- Avoid heat exposure (hot tubs, saunas).
First 24 Hours
- You may shower.
- Avoid strenuous exercise.
- Avoid prolonged sitting on hard surfaces if uncomfortable.
First 3 Days
- Avoid:
- Alcohol
- Smoking
- Anti-inflammatory medications (NSAIDs)
- Excessive heat exposure
- Continue good hydration.
Acetaminophen (Tylenol®) may be used for discomfort.
Sexual Activity
- Most patients may resume intercourse within 24 hours.
- If tenderness persists, wait until comfortable.
When Should I Call the Clinic?
Contact us if you experience:
- Severe swelling
- Increasing pain
- Fever
- Unusual discharge
- Persistent bleeding
Tips for Maximizing Results
- Stay hydrated.
- Avoid smoking.
- Consider pelvic floor therapy if indicated.
- Maintain hormonal balance (estrogen/testosterone optimization may enhance results).
- Follow up if booster treatments are recommended.
Who Is a Good Candidate?
Women experiencing:
- Decreased libido
- Difficulty achieving orgasm
- Vaginal dryness
- Mild stress urinary incontinence
- Postpartum tissue changes
- Perimenopausal or menopausal changes
Who Should Avoid Treatment?
- Active infection
- Pregnancy
- Platelet disorders
- Uncontrolled medical conditions
A full consultation is required prior to treatment.
Final Thoughts
The O-Shot is a regenerative, minimally invasive option for women seeking improved sexual wellness and tissue health. Results vary, but many patients report meaningful improvement in sensitivity, function, and confidence.
Want a printable copy?
Download the O-Shot® (PRP/PRF) Pre + Post Care Guide (PDF)
Nervana Medical · Sandy, UT · 801-335-5243 · nervanamedical.com